Guanidinoacetic acid with creatine compared with creatine alone for tissue creatine content, hyperhomocysteinemia, and exercise performance: A randomized, double-blind superiority trial
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چکیده
منابع مشابه
A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease
Background: Creatine and minocycline were prioritized for testing in Phase II clinical trials based on a systematic evaluation of potentially disease modifying compounds for Parkinson disease (PD). Objective: To test whether creatine and minocycline alter the course of early PD relative to a predetermined futility threshold for progression of PD in a randomized, double-blind, Phase II futility ...
متن کاملA randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease.
BACKGROUND Creatine and minocycline were prioritized for testing in Phase II clinical trials based on a systematic evaluation of potentially disease modifying compounds for Parkinson disease (PD). OBJECTIVE To test whether creatine and minocycline alter the course of early PD relative to a predetermined futility threshold for progression of PD in a randomized, double-blind, Phase II futility ...
متن کاملA randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease
Background: Creatine and minocycline were prioritized for testing in Phase II clinical trials based on a systematic evaluation of potentially disease modifying compounds for Parkinson disease (PD). Objective: To test whether creatine and minocycline alter the course of early PD relative to a predetermined futility threshold for progression of PD in a randomized, double-blind, Phase II futility ...
متن کاملCreatine supplementation and exercise performance: an update.
Creatine, a natural nutrient found in animal foods, is alleged to be an effective nutritional ergogenic aid to enhance sport or exercise performance. Research suggests that oral creatine monohydrate supplementation may increase total muscle creatine [TCr], including both free creatine [FCr] and phosphocreatine [PCr]. Some, but not all, studies suggest that creatine supplementation may enhance p...
متن کاملCreatine supplementation in fibromyalgia: a randomized, double-blind, placebo-controlled trial.
OBJECTIVE To investigate the efficacy and safety of creatine supplementation in fibromyalgia patients. METHODS A 16-week, randomized, double-blind, placebo-controlled, parallel-group trial was conducted. Fibromyalgia patients were randomly assigned to receive either creatine monohydrate or placebo in a double-blind manner. The patients were evaluated at baseline and after 16 weeks. Muscle fun...
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ژورنال
عنوان ژورنال: Nutrition
سال: 2019
ISSN: 0899-9007
DOI: 10.1016/j.nut.2018.04.009